UPT Promotes Technological Innovations in Safety Detection Across Multiple Fields

What is Up-Converting Phosphor Technology?

Up-converting phosphor technology (UPT) is a new type of labeling technology developed based on up-converting phosphor (UCP) materials. UCPs are nano-scale particles composed of several rare earth metal elements doped into certain crystal lattices. Due to their unique structure, UCPs can be excited by infrared light to emit visible light—up-converting. This unique property gives UCPs significant advantages as markers in bioanalysis, such as no background interference, no quenching, suitability for multiplex analysis and quantitative analysis, fundamentally different from traditional markers.

Applications of Up-Converting Phosphor Technology

On-site Biological Terrorism Detection, Ensuring Border Security

On-site biological terrorism detection is one of the most demanding and challenging applications. Due to the complexity of specimens, which may include decayed animal organs, samples mixed with mud, and foul-smelling liquid cultures (acidic liquids with low pH values), typical colloidal gold rapid tests cannot eliminate interference effects. Operators are often soldiers or quarantine personnel, so the operation must be simple, and the results and data must be accurate.

The UPT biosensor has undergone systematic evaluation for on-site application performance across various provinces and cities such as Xinjiang, Qinghai, Yunnan, Guangdong, Beijing, Shandong, and Inner Mongolia CDCs. It has also been used in numerous national major events for biosecurity, promoted to units such as the Beijing Municipal Health Bureau's CDC system, the Chinese Academy of Inspection and Quarantine, the firefighting system, the Chemical Research Institute, and the plague prevention system for on-site rapid detection of pathogens like anthrax, plague, and brucellosis. It has been utilized for security in large events such as the 2008 Beijing Olympics, 2009 Harbin Winter Universiade, the 60th Anniversary National Day celebrations, 2010 Shanghai World Expo, 2010 Guangzhou Asian Games, 2014 Beijing APEC meeting, 2017 Xiamen BRICS Conference, 2017 19th National Congress, 2018 Boao Forum for Asia, and 2018 SCO Summit.

Assisting Food Safety Testing, Ensuring "Food Safety"

There is substantial research both domestically and internationally on UPT in food safety testing. In China, UPT kit tests have achieved rapid quantitative detection of various foodborne pathogens such as E. coli O157, Vibrio cholerae O1/O139, Staphylococcus aureus, Vibrio parahaemolyticus, Listeria monocytogenes, Salmonella, and mycotoxins like aflatoxins, zearalenone, and vomitoxin. Compared to colloidal gold technology, this method offers high throughput advantages and can quickly detect contaminating bacteria in food and environmental samples with better results.

Handheld Hair Drug Testing, Making Hidden Drug Use Visible

Current common rapid drug testing methods include urine and saliva tests, both of which have short detection periods, significant drug interference, and sample preservation issues. Using hair as a sample not only resolves the issue of difficult urine collection but also avoids drug interference. Hair testing has a long detection period and can monitor whether a drug user has a history of drug use, establishing a database to guide law enforcement for more detailed monitoring work.

The handheld hair drug analyzer, using up-converting phosphor technology, has established a method for detecting common drugs. It can quickly perform quantitative and qualitative analysis of common drugs (morphine, methamphetamine, and ketamine) in hair. The detection limits for morphine, methamphetamine, and ketamine are 0.1 ng/mg, with a linear range of 0.1-100 ng/mg. This handheld hair drug analyzer offers simple, fast, accurate, and stable sample processing with high sensitivity; its accompanying sample reagents can be stored at room temperature, making it suitable for on-site use by public security and anti-drug enforcement personnel.

Hotgen masters the core technology of UPT, owning over 20 domestic and international patents. Its industrialization and market application levels are globally leading. Whether in biological anti-terrorism, food safety, or drug detection, Hotgen's technological innovations (like UPT kits and UPT devices) can provide strong support for public safety. If you require efficient and accurate detection solutions, Hotgen is undoubtedly a trustworthy choice.